Acetate → ethyl N-(benzyloxycarbonyl)piperidin-4-ylmethoxyacetate

HRID 2149879Notes

Reaction equation

HRID 2149879 reaction equation
[C:27]([O-:28])(=[O:29])[CH3:30].[C:31]([O-:32])(=[O:33])[CH3:34].[C:35]([O-:36])(=[O:37])[CH3:38].[C:39]([O-:40])(=[O:41])[CH3:42].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([CH2:17][OH:18])[CH2:15][CH2:16]1.[Cl:45][CH2:46][Cl:47].[N+:19](=[N-:20])=[CH:21][C:22](=[O:23])[O:24][CH2:25][CH3:26].[Rh+3:43].[Rh+3:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([CH2:17][O:18][CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 175Acetate4×HCID 6344DichloromethaneHCID 12192Ethyl diazoacetateHCID 167511Rhodium(3+)2×HCID 736490Benzyl 4-(hydroxymethyl)piperidine-1-carboxylate

Product 1

HCID 23370014ethyl N-(benzyloxycarbonyl)piperidin-4-ylmethoxyacetate

Sources & evidence

ORD record
ord-2941d558343c47659f38b9ed8131829b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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