3-Bromo-1-propanol → 3-[2-(2-methoxyethyl)-4-[2-(trifluoromethyl)-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepin-4-yl]piperazin-1-yl]propan-1-ol

HRID 2149963Notes

Reaction equation

HRID 2149963 reaction equation
[Br:29][CH2:30][CH2:31][CH2:32][OH:33].[CH3:1][O:2][CH2:3][CH2:4][CH:5]1[CH2:6][N:7]([C:11]2=[N:12][c:13]3[c:14]([cH:25][cH:26][cH:27][cH:28]3)[NH:15][c:16]3[s:17][c:18]([C:21]([F:22])([F:23])[F:24])[n:19][c:20]32)[CH2:8][CH2:9][NH:10]1>>[CH3:1][O:2][CH2:3][CH2:4][CH:5]1[CH2:6][N:7]([C:11]2=[N:12][c:13]3[c:14]([cH:25][cH:26][cH:27][cH:28]3)[NH:15][c:16]3[s:17][c:18]([C:21]([F:22])([F:23])[F:24])[n:19][c:20]32)[CH2:8][CH2:9][N:10]1[CH2:30][CH2:31][CH2:32][OH:33]

Participants

3

Reactant 2

HCID 123083-Bromo-1-propanolHCID 136384216HCID 136384216, compound

Product 1

HCID 1363947393-[2-(2-methoxyethyl)-4-[2-(trifluoromethyl)-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepin-4-yl]piperazin-1-yl]propan-1-ol

Sources & evidence

ORD record
ord-fcd38bf0719b457c9341fb6640983cf3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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