4-bromo-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1-pentyl-1,3-dihydro-2H-indol-2-one → 4'-bromo-1'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)one

HRID 2149966Notes

Reaction equation

HRID 2149966 reaction equation
[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:5](=[O:16])[C:4]2([CH2:17][OH:18])[c:19]1[cH:20][c:21]2[c:22]([cH:26][c:27]1[OH:28])[O:23][CH2:24][O:25]2.[CH:29]1([CH2:30][CH2:31][N:32]2[c:33]3[c:34]([cH:35][cH:36][cH:37][cH:38]3)[C:39]([c:40]3[c:41]([OH:42])[cH:43][c:44]4[c:48]([cH:49]3)[O:47][CH2:46][O:45]4)([CH2:50][OH:51])[C:52]2=[O:53])[CH2:54][CH2:55]1>>[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[N:6]([CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:5](=[O:16])[C:4]21[CH2:17][O:18][c:27]2[c:19]1[cH:20][c:21]1[c:22]([cH:26]2)[O:23][CH2:24][O:25]1

Participants

3

Reactant 2

HCID 588725244-bromo-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1-pentyl-1,3-dihydro-2H-indol-2-oneHCID 666425671-(2-cyclopropylethyl)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one

Product 1

HCID 592633394'-bromo-1'-pentylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)one

Sources & evidence

ORD record
ord-baaaf0bb5c5544a2af79c9ce1f6854cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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