Dichloromethane → 5-(4-(Chloromethyl)benzyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

HRID 2150004Notes

Reaction equation

HRID 2150004 reaction equation
[Cl:28][CH2:29][Cl:30].[NH2:5][c:6]1[n:7][c:8]([NH:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[c:9]([CH2:13][c:14]2[cH:15][cH:16][c:17]([CH2:20][OH:21])[cH:18][cH:19]2)[c:10]([CH3:12])[n:11]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][CH2:20][c:17]1[cH:16][cH:15][c:14]([CH2:13][c:9]2[c:8]([NH:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[n:7][c:6]([NH2:5])[n:11][c:10]2[CH3:12])[cH:19][cH:18]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 68416750(4-((2-Amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)methanol

Product 1

HCID 684164415-(4-(Chloromethyl)benzyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-54ac3ce6a2be4a65a7fa1ce85c7bb57f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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