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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2150314Generated: November 4, 2026

Hydrochloric Acid → 4-(4-(1-(2-(Dimethylamino)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidin-1-yl)-7-(4-methoxybenzyl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

https://huagongshe.com/reaction/2150314

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-methyl-2-pyrrolidoneHCID 13387—
ReactantDiisopropylethylamineHCID 81531—
ReactantN,N-Dimethyl-2-(piperidine-4-yl)-4-[3-(trifluoromethyl)-4-fluorophenyl]-1H-imidazole-1-ethanamineHCID 60194946—
Reactant4-Chloro-7-(4-methoxybenzyl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-oneHCID 86641610—
Product4-(4-(1-(2-(Dimethylamino)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidin-1-yl)-7-(4-methoxybenzyl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-oneHCID 67265086—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-0ac9e9472fe546e4a5c4d2feba3b6fbd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)