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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2150411Generated: October 25, 2026

1,4-Oxazepane → N-(4-{4-amino-7-[3-(1,4-oxazepan-4-yl)propyl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2-fluorophenyl)-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea

https://huagongshe.com/reaction/2150411

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-OxazepaneHCID 21873275—
Reactant1-{4-[4-Amino-7-(3-bromopropyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl]-2-fluorophenyl}-3-[2-fluoro-5-(trifluoromethyl)phenyl]ureaHCID 59231947—
Reactant1-[4-[4-Amino-7-[3-[2-(methoxymethyl)pyrrolidin-1-yl]propyl]pyrrolo[2,1-f][1,2,4]triazin-5-yl]-2-fluorophenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]ureaHCID 68096963—
ProductN-(4-{4-amino-7-[3-(1,4-oxazepan-4-yl)propyl]pyrrolo[2,1-f][1,2,4]triazin-5-yl}-2-fluorophenyl)-N'-[2-fluoro-5-(trifluoromethyl)phenyl]ureaHCID 59232073—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-97ae12dc93b041c182dee10cae06e58d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)