Acetate → tert-butyl N-[4-[[1-cyano-2-[4-(1-oxo-2,3-dihydroisoindol-5-yl)phenyl]ethyl]carbamoyl]oxan-4-yl]carbamate
Reaction equation
[C:1](#[N:2])[CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[C:15]1([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1.[CH3:30][C:31](=[O:32])[O-:33].[CH3:34][C:35]1([CH3:36])[C:37]([CH3:38])([CH3:39])[O:40][B:41]([c:42]2[cH:43][c:44]3[c:48]([cH:49][cH:50]2)[C:47](=[O:51])[NH:46][CH2:45]3)[O:52]1.[CH3:53][C:54]#[N:55].[K+:29].[OH2:56]>>[C:1](#[N:2])[CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:42]2[cH:43][c:44]3[c:48]([cH:49][cH:50]2)[C:47](=[O:51])[NH:46][CH2:45]3)[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[C:15]1([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1c295da797d14540a867a7d182aba578
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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