Formic Acid → 4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[(1-methylpyrrolidin-3-yl)oxy]quinazoline
Reaction equation
[CH2:35]=[O:36].[CH:37]([OH:38])=[O:39].[Cl:1][c:2]1[c:3]([F:34])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:29][CH3:30])[c:13]([O:16][CH:17]4[CH2:18][N:19]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:20][CH2:21]4)[cH:14][c:15]23)[cH:31][cH:32][cH:33]1>>[Cl:1][c:2]1[c:3]([F:34])[c:4]([NH:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:29][CH3:30])[c:13]([O:16][CH:17]4[CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]4)[cH:14][c:15]23)[cH:31][cH:32][cH:33]1Participants
4
Sources & evidence
- ORD record
- ord-96b51aef236548e1be350f5ec20239f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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