2-Bromo-4,8-dimethylquinoline → 4-((4,8-Dimethylquinolin-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile
Reaction equation
[Br:36][c:37]1[n:38][c:39]2[c:40]([CH3:48])[cH:41][cH:42][cH:43][c:44]2[c:45]([CH3:47])[cH:46]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[n:8][c:9]([N:12]([c:13]1[cH:14][cH:15][c:16]([C:17]#[N:18])[cH:19][cH:20]1)[CH2:21][c:22]1[c:23]([F:35])[c:24]([O:31][CH:32]([CH3:33])[CH3:34])[cH:25][c:26]([O:28][CH2:29][CH3:30])[cH:27]1)[cH:10][cH:11]2>>[N:12]([c:13]1[cH:14][cH:15][c:16]([C:17]#[N:18])[cH:19][cH:20]1)([CH2:21][c:22]1[c:23]([F:35])[c:24]([O:31][CH:32]([CH3:33])[CH3:34])[cH:25][c:26]([O:28][CH2:29][CH3:30])[cH:27]1)[c:37]1[n:38][c:39]2[c:40]([CH3:48])[cH:41][cH:42][cH:43][c:44]2[c:45]([CH3:47])[cH:46]1Participants
3
Sources & evidence
- ORD record
- ord-e24002aad8964c09910f886ed1b05f2a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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