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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2151619Generated: October 27, 2026

Hydrochloric Acid → 4-fluoro-N-((1RS,2SR)-2-hydroxy-2-(1-naphthalenyl)-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)-1-naphthalenecarboxamide

https://huagongshe.com/reaction/2151619

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantOxalyl chlorideHCID 65578—
Reactant4-Fluoro-1-naphthoic acidHCID 68448—
Reactant2-Amino-1-naphthalen-1-yl-3-[4-(trifluoromethyl)phenyl]propan-1-olHCID 69553921—
Product4-fluoro-N-((1RS,2SR)-2-hydroxy-2-(1-naphthalenyl)-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)-1-naphthalenecarboxamideHCID 22261498—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b17757aa626647598227255e462c4510
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)