5-Amino-1-piperidin-1-yl-pentan-2-ol → 3-(2,5-difluoro-4-methyl-benzyloxy)-5-[3-(4-hydroxy-5-piperidin-1-yl-pentyl)-ureido]-isothiazole-4-carboxylic Acid Amide
Reaction equation
[NH2:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:35][N:36]1[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]1)[OH:42].[c:1]1([O:2][C:8]([NH:9][c:10]2[c:11]([C:26]([NH2:27])=[O:28])[c:12]([O:15][CH2:16][c:17]3[c:18]([F:25])[cH:19][c:20]([CH3:24])[c:21]([F:23])[cH:22]3)[n:13][s:14]2)=[O:29])[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[C:8]([NH:9][c:10]1[c:11]([C:26]([NH2:27])=[O:28])[c:12]([O:15][CH2:16][c:17]2[c:18]([F:25])[cH:19][c:20]([CH3:24])[c:21]([F:23])[cH:22]2)[n:13][s:14]1)(=[O:29])[NH:30][CH2:31][CH2:32][CH2:33][CH:34]([CH2:35][N:36]1[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]1)[OH:42]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e1cf30eac7894d488716ebed49fb3037
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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