4-Hydroxyproline → Methyl 4-hydroxypyrrolidine-2-carboxylate

HRID 2152334Notes

Reaction equation

HRID 2152334 reaction equation
[CH3:14][OH:15].[OH:5][CH:6]1[CH2:7][NH:8][CH:9]([C:11]([OH:12])=[O:13])[CH2:10]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[OH:5][CH:6]1[CH2:7][NH:8][CH:9]([C:11](=[O:12])[O:13][CH3:14])[CH2:10]1

Participants

4

Reactant 3

HCID 8254-HydroxyprolineHCID 887MethanolHCID 24386Thionyl Chloride

Product 1

HCID 549381Methyl 4-hydroxypyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-e66b9de570b54e399503284abc85fdd6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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