Ethyl 5-bromopyridine-3-carboxylate → Ethyl 5-(3,5-dimethylpiperazin-1-yl)pyridine-3-carboxylate

HRID 2152477Notes

Reaction equation

HRID 2152477 reaction equation
[Br:16][c:17]1[cH:18][c:19]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:20][n:21][cH:22]1.[Cl:1][c:2]1[cH:3][c:4]([N:8]2[CH2:9][CH:10]([CH3:15])[NH:11][CH:12]([CH3:14])[CH2:13]2)[cH:5][cH:6][n:7]1>>[N:8]1([c:17]2[cH:18][c:19]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:20][n:21][cH:22]2)[CH2:9][CH:10]([CH3:15])[NH:11][CH:12]([CH3:14])[CH2:13]1

Participants

3

Reactant 2

HCID 140785Ethyl 5-bromopyridine-3-carboxylateHCID 724825601-(2-Chloro-4-pyridinyl)-3,5-dimethylpiperazine

Product 1

HCID 68681497Ethyl 5-(3,5-dimethylpiperazin-1-yl)pyridine-3-carboxylate

Sources & evidence

ORD record
ord-17de86dd766b4f5ea147f45ea8872a4a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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