2'-Fluorobiphenyl-2-carboxylic acid → [3-[(5-Bromopyrimidin-2-yl)amino]piperidin-1-yl]-[2-(2-fluorophenyl)phenyl]methanone

HRID 2152550Notes

Reaction equation

HRID 2152550 reaction equation
[Br:17][c:18]1[cH:19][n:20][c:21]([NH:24][CH:25]2[CH2:26][NH:27][CH2:28][CH2:29][CH2:30]2)[n:22][cH:23]1.[F:1][c:2]1[c:3](-[c:8]2[c:9]([C:14](=[O:15])[OH:16])[cH:10][cH:11][cH:12][cH:13]2)[cH:4][cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:8]2[c:9]([C:14](=[O:16])[N:27]3[CH2:26][CH:25]([NH:24][c:21]4[n:20][cH:19][c:18]([Br:17])[cH:23][n:22]4)[CH2:30][CH2:29][CH2:28]3)[cH:10][cH:11][cH:12][cH:13]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 51092292'-Fluorobiphenyl-2-carboxylic acidHCID 63872105(5-Bromo-pyrimidin-2-yl)-piperidin-3-ylamine

Product 1

HCID 66639481[3-[(5-Bromopyrimidin-2-yl)amino]piperidin-1-yl]-[2-(2-fluorophenyl)phenyl]methanone

Sources & evidence

ORD record
ord-6c4d387ac9f8442094c282e4d9862d35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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