Acetonitrile → tert-Butyl 4-(4-amino-3-bromophenyl)-piperidine-1-carboxylate

HRID 2152610Notes

Reaction equation

HRID 2152610 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][cH:16][c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH3:29][C:30]#[N:31].[O:21]=[C:22]1[N:23]([Br:28])[C:24](=[O:25])[CH2:26][CH2:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][c:16]([Br:28])[c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 67184N-bromobutanimideHCID 21940085tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate

Product 1

HCID 56834849tert-Butyl 4-(4-amino-3-bromophenyl)-piperidine-1-carboxylate

Sources & evidence

ORD record
ord-6bbce52600ad413390718ec4f894f6fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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