Pyridine → Tert-butyl 3-[5-ethyl-6-[4-(5,6,7,8-tetrahydro-(1,8)naphthyridin-2-yl)-piperidin-1-yl]-pyrimidin-4-ylamino]-2-(4-methoxy benzoyl)-propionate
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[Cl:9])[cH:10][cH:11]1.[Cl:47][CH2:48][Cl:49].[NH2:12][CH:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:21][NH:22][c:23]1[n:24][cH:25][n:26][c:27]([N:31]2[CH2:32][CH2:33][CH:34]([c:37]3[n:38][c:39]4[c:44]([cH:45][cH:46]3)[CH2:43][CH2:42][CH2:41][NH:40]4)[CH2:35][CH2:36]2)[c:28]1[CH2:29][CH3:30].[cH:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[CH:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:21][NH:22][c:23]2[n:24][cH:25][n:26][c:27]([N:31]3[CH2:32][CH2:33][CH:34]([c:37]4[n:38][c:39]5[c:44]([cH:45][cH:46]4)[CH2:43][CH2:42][CH2:41][NH:40]5)[CH2:35][CH2:36]3)[c:28]2[CH2:29][CH3:30])[cH:10][cH:11]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-453c262c5a3f45bc8a5600f3ade3ce96
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…