Dichloromethane → 8-Bromo-3-(4-fluorobenzoyl)-1-methyl-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester

HRID 2152974Notes

Reaction equation

HRID 2152974 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[CH:7][N:8]([C:21]([c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)=[O:29])[CH2:9][CH:10]([CH3:20])[c:11]2[c:12]1[nH:13][c:14]1[cH:15][cH:16][cH:17][cH:18][c:19]21.[Cl:38][CH2:39][Cl:40].[O:30]=[C:31]1[N:32]([Br:37])[C:33](=[O:34])[CH2:35][CH2:36]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1=[CH:7][N:8]([C:21]([c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)=[O:29])[CH2:9][CH:10]([CH3:20])[c:11]2[c:12]1[nH:13][c:14]1[cH:15][c:16]([Br:37])[cH:17][cH:18][c:19]21

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 67184N-bromobutanimideHCID 10000577Ethyl 3-(4-fluorobenzoyl)-1-methyl-1,2,3,6-tetrahydro-azepino[4,5-b]indole-5-carboxylate

Product 1

HCID 113972798-Bromo-3-(4-fluorobenzoyl)-1-methyl-1,2,3,6-tetrahydroazepino[4,5-B]indole-5-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-efd397984dcd45e8b2454a62bc5145ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…