Chloroform → 3-ethyl-alpha-hydroxy-2,5-dihydro-5-oxo-1-phenyl-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl ester

HRID 2152977Notes

Reaction equation

HRID 2152977 reaction equation
[CH2:1]([CH3:2])[c:3]1[nH:4][n:5](-[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[c:6](=[O:8])[cH:7]1.[CH:25]([Cl:26])([Cl:27])[Cl:28].[F:15][C:16]([C:17]([C:18](=[O:19])[O:20][CH3:21])=[O:22])([F:23])[F:24]>>[CH2:1]([CH3:2])[c:3]1[nH:4][n:5](-[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[c:6](=[O:8])[c:7]1[C:17]([C:16]([F:15])([F:23])[F:24])([C:18](=[O:19])[O:20][CH3:21])[OH:22]

Participants

4

Reactant 3

HCID 6212ChloroformHCID 2734931Methyl 3,3,3-trifluoro-2-oxopropanoateHCID 138848095-Ethyl-2-phenyl-1,2-dihydro-pyrazol-3-one

Product 1

HCID 441396903-ethyl-alpha-hydroxy-2,5-dihydro-5-oxo-1-phenyl-alpha-trifluoromethyl-1H-pyrazole-4-acetic acid methyl ester

Sources & evidence

ORD record
ord-a847f2a61ffb4cfa82858086992aed47
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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