(2,4-Dimethoxypyrimidin-5-yl)boronic acid → N-(1-{1-[3-(2,4-Dimethoxy-pyrimidin-5-yl)-phenyl]-1H-benzoimidazol-5-yl}-ethyl)-formamide

HRID 2153130Notes

Reaction equation

HRID 2153130 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[cH:13][cH:14][c:15]([CH:17]([CH3:18])[NH:19][CH:20]=[O:21])[cH:16]3)[cH:5][cH:6][cH:7]1.[CH3:22][O:23][c:24]1[n:25][cH:26][c:27]([B:32]([OH:33])[OH:34])[c:28]([O:30][CH3:31])[n:29]1>>[c:2]1(-[c:27]2[cH:26][n:25][c:24]([O:23][CH3:22])[n:29][c:28]2[O:30][CH3:31])[cH:3][c:4](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[cH:13][cH:14][c:15]([CH:17]([CH3:18])[NH:19][CH:20]=[O:21])[cH:16]3)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 2736209(2,4-Dimethoxypyrimidin-5-yl)boronic acidHCID 57572242N-{1-[1-(3-Bromo-phenyl)-1H-benzoimidazol-5-yl]-ethyl}-formamide

Product 1

HCID 11983416N-(1-{1-[3-(2,4-Dimethoxy-pyrimidin-5-yl)-phenyl]-1H-benzoimidazol-5-yl}-ethyl)-formamide

Sources & evidence

ORD record
ord-f006bc659b55480aa842ddb0f45f0417
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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