Pyridine → 5-(ethoxyamino-methyl)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-benzamide
Reaction equation
[BH3:36].[CH2:1]([CH3:2])[O:3][N:4]=[CH:5][c:6]1[c:7]([F:29])[c:8]([F:28])[c:9]([NH:19][c:20]2[c:21]([F:27])[cH:22][c:23]([I:26])[cH:24][cH:25]2)[c:10]([C:11](=[O:12])[NH:13][O:14][CH2:15][CH2:16][OH:17])[cH:18]1.[OH:37][C:38]([CH:39]([Cl:40])[Cl:41])=[O:42].[n:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[CH2:1]([CH3:2])[O:3][NH:4][CH2:5][c:6]1[c:7]([F:29])[c:8]([F:28])[c:9]([NH:19][c:20]2[c:21]([F:27])[cH:22][c:23]([I:26])[cH:24][cH:25]2)[c:10]([C:11](=[O:12])[NH:13][O:14][CH2:15][CH2:16][OH:17])[cH:18]1Participants
5
Sources & evidence
- ORD record
- ord-58bae08bae564d098a6fcdc09d9a003e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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