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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2153638Generated: November 2, 2026

Dimethylformamide → 5-(4-Fluoro-3-hydroxy-benzylcarbamoyl)-3-methyl-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/2153638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant5-(Aminomethyl)-2-fluorophenolHCID 20776986—
Reactant5-(Methoxycarbonyl)-4-methylthiophene-2-carboxylic acidHCID 68226619—
Product5-(4-Fluoro-3-hydroxy-benzylcarbamoyl)-3-methyl-thiophene-2-carboxylic acid methyl esterHCID 68226833—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-d7eff0a7bf8045b992535c16cc2c4286
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)