8-[(3-Methyl-2-thienyl)methyl]-2,8-diazaspiro[4.5]decane → 3-(1H-imidazol-2-yl)-2-(1H-imidazol-2-ylmethyl)-1-[4-({8-[(3-methyl-2-thienyl)methyl]-2,8-diazaspiro[4.5]dec-2-yl}methyl)phenyl]propan-1-one
Reaction equation
[CH3:1][c:2]1[c:3]([CH2:7][N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][CH2:13][NH:14][CH2:15]3)[CH2:16][CH2:17]2)[s:4][cH:5][cH:6]1.[nH:18]1[c:19]([CH2:23][CH:24]([C:25](=[O:26])[c:27]2[cH:28][cH:29][c:30]([CH:31]=[O:32])[cH:33][cH:34]2)[CH2:35][c:36]2[nH:37][cH:38][cH:39][n:40]2)[n:20][cH:21][cH:22]1>>[CH3:1][c:2]1[c:3]([CH2:7][N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][CH2:13][N:14]([CH2:31][c:30]4[cH:29][cH:28][c:27]([C:25]([CH:24]([CH2:23][c:19]5[nH:18][cH:22][cH:21][n:20]5)[CH2:35][c:36]5[nH:37][cH:38][cH:39][n:40]5)=[O:26])[cH:34][cH:33]4)[CH2:15]3)[CH2:16][CH2:17]2)[s:4][cH:5][cH:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6f53254e3bc046578bc7eb1f9534520b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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