Ammonium → 1,1-Dimethylethyl 4-[5-(2-amino-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-4-methyl-1-piperidinecarboxylate
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:27]3[c:28]([F:45])[c:29]([NH:33][S:34](=[O:35])(=[O:36])[c:37]4[c:38]([F:44])[cH:39][cH:40][cH:41][c:42]4[F:43])[cH:30][cH:31][cH:32]3)[n:10][c:11]([C:13]3([CH3:26])[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1.[NH4+:46].[OH-:47]>>[c:2]1([NH2:46])[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:27]3[c:28]([F:45])[c:29]([NH:33][S:34](=[O:35])(=[O:36])[c:37]4[c:38]([F:44])[cH:39][cH:40][cH:41][c:42]4[F:43])[cH:30][cH:31][cH:32]3)[n:10][c:11]([C:13]3([CH3:26])[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2c2a52d33d61413aab17532682148270
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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