Acetate → 4'-Chlorobiphenyl-2-carbaldehyde

HRID 2153968Notes

Reaction equation

HRID 2153968 reaction equation
[Br:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1.[C:20](=[O:21])([O-:22])[O-:23].[C:44]([O-:45])(=[O:46])[CH3:47].[C:49]([O-:50])(=[O:51])[CH3:52].[CH2:27]([N+:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH3:54][C:55]([CH3:56])=[O:57].[Cl:10][c:11]1[cH:12][cH:13][c:14]([B:17]([OH:18])[OH:19])[cH:15][cH:16]1.[I-:26].[K+:24].[K+:25].[OH2:53].[Pd+2:48]>>[c:2]1(-[c:14]2[cH:13][cH:12][c:11]([Cl:10])[cH:16][cH:15]2)[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1

Participants

11

Reactant 10

HCID 175Acetate2×HCID 180AcetoneHCID 813Potassium Cation2×HCID 962WaterHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 30165Iodide IonHCID 742994-Chlorophenylboronic acidHCID 811292-BromobenzaldehydeHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 13936894'-Chlorobiphenyl-2-carbaldehyde

Sources & evidence

ORD record
ord-98d82303855947b9b644a38345a5604f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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