3-Aminophenol → N4-(4-ethoxyphenyl)-N2-(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine

HRID 2154124Notes

Reaction equation

HRID 2154124 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][CH3:17])[cH:13][cH:14]2)[n:7]1.[OH:19][c:20]1[cH:21][c:22]([NH2:23])[cH:24][cH:25][cH:26]1>>[c:2]1([NH:23][c:22]2[cH:21][c:20]([OH:19])[cH:26][cH:25][cH:24]2)[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][CH3:17])[cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 115683-AminophenolHCID 220606042-chloro-N4-(4-ethoxyphenyl)-5-fluoro-4-pyrimidineamine

Product 1

HCID 22060751N4-(4-ethoxyphenyl)-N2-(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-f1403921c74144c6a2f70593c9a3c2dc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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