2-Chloro-4-hydroxybenzaldehyde → 2-[3-Chloro-4-({[4-trifluoromethyl-2-(4-trifluoromethyl-phenyl)-pyrimidine-5-carbonyl]-amino}-methyl)-phenoxy]-2-methyl-propionic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]([Cl:17])[c:12]([CH2:15][NH2:16])[cH:13][cH:14]1)=[O:18].[CH2:29]([CH2:30][C:31]([Br:32])([CH3:33])[C:34]([O-:35])=[O:36])[CH3:37].[CH2:61]([O:62][C:63]([c:64]1[c:65]([C:66]([F:67])([F:68])[F:69])[n:70][c:71](-[c:72]2[cH:73][cH:74][c:75]([C:76]([F:77])([F:78])[F:79])[cH:80][cH:81]2)[n:82][cH:83]1)=[O:84])[CH3:85].[Cl:19][c:20]1[cH:21][c:22]([OH:23])[cH:24][cH:25][c:26]1[CH:27]=[O:28].[F:38][C:39]([c:40]1[n:41][c:42](-[c:49]2[cH:50][cH:51][c:52]([C:55]([F:56])([F:57])[F:58])[cH:53][cH:54]2)[n:43][cH:44][c:45]1[C:46](=[O:47])[OH:48])([F:59])[F:60]>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]([Cl:17])[c:12]([CH2:15][NH:16][C:46]([c:45]2[c:40]([C:39]([F:38])([F:59])[F:60])[n:41][c:42](-[c:49]3[cH:50][cH:51][c:52]([C:55]([F:56])([F:57])[F:58])[cH:53][cH:54]3)[n:43][cH:44]2)=[O:47])[cH:13][cH:14]1)=[O:18]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5bc4101aa2264964bf7360dc9505f874
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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