3,3-Dimethylbutanoyl chloride → 3,3-Dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one

HRID 2154291Notes

Reaction equation

HRID 2154291 reaction equation
[C:32]([CH3:33])([CH3:34])([CH3:35])[CH2:36][C:37](=[O:38])[Cl:39].[CH3:1][c:2]1[cH:3][c:4]([NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[cH:22][n:23][c:24]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[cH:25]3)[cH:5][cH:6][c:7]1[O:8][CH:9]1[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]1>>[CH3:1][c:2]1[cH:3][c:4]([NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[cH:22][n:23][c:24]([N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[cH:25]3)[cH:5][cH:6][c:7]1[O:8][CH:9]1[CH2:10][CH2:11][N:12]([C:37]([CH2:36][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:38])[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 815143,3-Dimethylbutanoyl chlorideHCID 69057517[3-Methyl-4-(piperidin-4-yloxy)-phenyl]-(6-morpholin-4-yl-pyrido[3,4-d]pyrimidin-4-yl)-amine

Product 1

HCID 444262793,3-Dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one

Sources & evidence

ORD record
ord-d9cd6ea451eb496eb5e3df675d063851
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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