4-(2-Propyn-1-yl)morpholine → {2-Methyl-4-[3-(3-morpholin-4-yl-prop-1-ynyl)-5-(3-trifluoromethyl-pyridin-2-yloxy)-phenylsulfanyl]-phenoxy}-acetic Acid Ethyl Ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][O:6][c:7]1[c:8]([CH3:32])[cH:9][c:10]([S:13][c:14]2[cH:15][c:16]([Br:31])[cH:17][c:18]([O:20][c:21]3[n:22][cH:23][cH:24][cH:25][c:26]3[C:27]([F:28])([F:29])[F:30])[cH:19]2)[cH:11][cH:12]1)=[O:33].[CH2:34]([C:35]#[CH:36])[N:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[CH2:43]([O:44][C:45](=[O:46])[CH2:47][O:48][c:49]1[cH:50][cH:51][c:52]([S:53][c:54]2[cH:55][c:56]([C:57]#[C:58][c:59]3[cH:60][cH:61][c:62]([CH2:63][OH:64])[cH:65][cH:66]3)[cH:67][c:68]([O:69][CH2:70][CH2:71][c:72]3[cH:73][cH:74][c:75]([Cl:76])[cH:77][cH:78]3)[cH:79]2)[cH:80][c:81]1[CH3:82])[CH3:83]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][O:6][c:7]1[c:8]([CH3:32])[cH:9][c:10]([S:13][c:14]2[cH:15][c:16]([C:36]#[C:35][CH2:34][N:37]3[CH2:38][CH2:39][O:40][CH2:41][CH2:42]3)[cH:17][c:18]([O:20][c:21]3[n:22][cH:23][cH:24][cH:25][c:26]3[C:27]([F:28])([F:29])[F:30])[cH:19]2)[cH:11][cH:12]1)=[O:33]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-99f0446b419844e588155ff31712d31d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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