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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2154613Generated: October 26, 2026

Tetrahydrofuran → 3-(2,4-Dichloro-pyrimidin-5-yl)-2-(3,5-dimethoxy-phenyl)-propionic acid methyl ester

https://huagongshe.com/reaction/2154613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantCyclohexylisopropylamineHCID 62386—
ReactantMethyl 3,5-dimethoxyphenylacetateHCID 592191—
Reactant2,4-Dichloro-5-(iodomethyl)pyrimidineHCID 21939352—
ReactantButyllithiumHCID 178418339—
Product3-(2,4-Dichloro-pyrimidin-5-yl)-2-(3,5-dimethoxy-phenyl)-propionic acid methyl esterHCID 21044320—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-42ee382c03004708994f56761d3482d6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)