Ethanol → 6-Bromo-7-fluoro-2-phenylchroman-4-one

HRID 2154771Notes

Reaction equation

HRID 2154771 reaction equation
[Br:1][c:2]1[c:3]([F:19])[cH:4][c:5]([OH:18])[c:6]([C:8]([CH:9]=[CH:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)=[O:17])[cH:7]1.[CH3:23][CH2:24][OH:25].[Na+:21].[OH-:20].[OH2:22]>>[Br:1][c:2]1[c:3]([F:19])[cH:4][c:5]2[c:6]([cH:7]1)[C:8](=[O:17])[CH2:9][CH:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[O:18]2

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 671755841-(5-Bromo-4-fluoro-2-hydroxyphenyl)-3-phenylprop-2-en-1-one

Product 1

HCID 584240016-Bromo-7-fluoro-2-phenylchroman-4-one

Sources & evidence

ORD record
ord-e25b72ccdcf04fba8c639310c9d7e974
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…