4-(2-(Pyrrolidin-1-yl)ethoxy)aniline → N(8)-(2-Methanesulfonyl-phenyl)-N(2)-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

HRID 2154793Notes

Reaction equation

HRID 2154793 reaction equation
[CH:37]1([P:38]([CH:39]2[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][c:50]2-[c:51]2[cH:52][cH:53][cH:54][cH:55][c:56]2[P:57]([CH:58]2[CH2:59][CH2:60][CH2:61][CH2:62][CH2:63]2)[CH:64]2[CH2:65][CH2:66][CH2:67][CH2:68][CH2:69]2)[CH2:70][CH2:71][CH2:72][CH2:73][CH2:74]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6]([NH:10][c:11]3[c:12]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:13][cH:14][cH:15][cH:16]3)[cH:7][cH:8][cH:9]2)[n:21]1.[N:22]1([CH2:27][CH2:28][O:29][c:30]2[cH:31][cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[CH2:23][CH2:24][CH2:25][CH2:26]1>>[c:2]1([NH:36][c:33]2[cH:32][cH:31][c:30]([O:29][CH2:28][CH2:27][N:22]3[CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:35][cH:34]2)[n:3][n:4]2[c:5]([c:6]([NH:10][c:11]3[c:12]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:13][cH:14][cH:15][cH:16]3)[cH:7][cH:8][cH:9]2)[n:21]1

Participants

4

Reactant 3

HCID 64937494-(2-(Pyrrolidin-1-yl)ethoxy)anilineHCID 249469872,2'-Bis(dicyclohexylphosphino)-1,1'-biphenylHCID 67478992(2-Chloro-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-(2-methanesulfonyl-phenyl)-amine

Product 1

HCID 67478884N(8)-(2-Methanesulfonyl-phenyl)-N(2)-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

Sources & evidence

ORD record
ord-b344583577a44066924cc8fbe387e85a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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