Methanol → 1-[1-(2-Methoxy-phenyl)-cyclobutyl]-2-[3-(4-trifluoromethyl-phenoxymethyl)-piperidin-1-yl]-ethanol
Reaction equation
[BH4-:34].[CH3:1][O:2][c:3]1[c:4]([C:9]2([C:13]([CH2:14][N:15]3[CH2:16][CH:17]([CH2:21][O:22][c:23]4[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]4)[CH2:18][CH2:19][CH2:20]3)=[O:33])[CH2:10][CH2:11][CH2:12]2)[cH:5][cH:6][cH:7][cH:8]1.[CH3:37][OH:38].[Na+:35].[OH2:36]>>[CH3:1][O:2][c:3]1[c:4]([C:9]2([CH:13]([CH2:14][N:15]3[CH2:16][CH:17]([CH2:21][O:22][c:23]4[cH:24][cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]4)[CH2:18][CH2:19][CH2:20]3)[OH:33])[CH2:10][CH2:11][CH2:12]2)[cH:5][cH:6][cH:7][cH:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-56f77925f8d34a9ba168af60cb41a7ea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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