Dichloromethane → 4-((5-Chloro-3-methyl-pyridin-2-ylmethyl)-{3-[1-(4-fluoro-phenyl)-1-methyl-ethyl]-pyridin-2-ylmethyl}-amino)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][CH:29]([NH:32][CH2:33][c:34]2[n:35][cH:36][c:37]([Cl:41])[cH:38][c:39]2[CH3:40])[CH2:30][CH2:31]1.[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH3:9])([CH3:10])[c:11]2[c:12]([CH:17]=[O:18])[n:13][cH:14][cH:15][cH:16]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH3:9])([CH3:10])[c:11]2[c:12]([CH2:17][N:32]([CH:29]3[CH2:28][CH2:27][N:26]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:25])[CH2:31][CH2:30]3)[CH2:33][c:34]3[n:35][cH:36][c:37]([Cl:41])[cH:38][c:39]3[CH3:40])[n:13][cH:14][cH:15][cH:16]2)[cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-58e2a8f701194b4b8a2859626351b192
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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