Methanol → 3-[1-(6,7-Dimethoxy-4-quinazolinyl)-4-piperidinyl]-1,2,3,4-tetrahydro-6-(1-hydroxyethyl)-1-methyl-2,4-dioxoquinazoline
Reaction equation
[BH4-:43].[C:7]([CH3:8])(=[O:9])[c:10]1[cH:11][c:12]2[c:13](=[O:42])[n:14]([CH:22]3[CH2:23][CH2:24][N:25]([c:28]4[n:29][cH:30][n:31][c:32]5[cH:33][c:34]([O:40][CH3:41])[c:35]([O:38][CH3:39])[cH:36][c:37]45)[CH2:26][CH2:27]3)[c:15](=[O:21])[n:16]([CH3:20])[c:17]2[cH:18][cH:19]1.[CH3:1][OH:2].[CH:3]([Cl:4])([Cl:5])[Cl:6].[Na+:44].[OH2:45]>>[CH:7]([CH3:8])([OH:9])[c:10]1[cH:11][c:12]2[c:13](=[O:42])[n:14]([CH:22]3[CH2:23][CH2:24][N:25]([c:28]4[n:29][cH:30][n:31][c:32]5[cH:33][c:34]([O:40][CH3:41])[c:35]([O:38][CH3:39])[cH:36][c:37]45)[CH2:26][CH2:27]3)[c:15](=[O:21])[n:16]([CH3:20])[c:17]2[cH:18][cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a6522dfc97f64fab9afeea81894ae0a5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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