反应详情

温度

0 °C

11.1 g of pyridinium chlorochromate and 12 g of Celite were suspended in 100 ml of dry dichloromethane, and 6 g of (Z)-4-benzyloxy-2-buten-1-ol was added thereto at 0° C. under stirring. The mixture was stirred at room temperature for 3 hours. Diethyl ether was added thereto, and insolubles were removed by filtration. The filtrate was distilled under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography (diethyl ether) to obtain 3.9 g of (Z)-4-benzyloxy-2-butenal as slightly yellow oily substance.

1. stirringThe mixture was stirred at room temperature for 3 hours
2. custominsolubles were removed by filtration
3. distillationThe filtrate was distilled under reduced pressure
4. customto remove the solvent
5. customthe residue was purified by silica gel column chromatography (diethyl ether)