Imidazole → 6-Fluoro-2-methyl-8-(triisopropylsilyloxy)quinoline

HRID 2155335Notes

Reaction equation

[CH2:37]([Cl:38])[Cl:39].[F:19][C:20]([F:21])([F:22])[S:23]([O:24][Si:25]([CH:26]([CH3:27])[CH3:28])([CH:29]([CH3:30])[CH3:31])[CH:32]([CH3:33])[CH3:34])(=[O:35])=[O:36].[F:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([CH3:13])[n:8][c:9]2[c:10]([OH:12])[cH:11]1.[nH:14]1[cH:15][cH:16][n:17][cH:18]1>>[F:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][c:7]([CH3:13])[n:8][c:9]2[c:10]([O:12][Si:25]([CH:26]([CH3:27])[CH3:28])([CH:29]([CH3:30])[CH3:31])[CH:32]([CH3:33])[CH3:34])[cH:11]1

Participants

Reactant 4

HCID 795Imidazole

HCID 6344Dichloromethane

HCID 2724529Triisopropylsilyl trifluoromethanesulfonate

HCID 667815176-Fluoro-8-hydroxy-2-methylquinoline

Product 1

HCID 667814296-Fluoro-2-methyl-8-(triisopropylsilyloxy)quinoline

Sources & evidence

ORD record: ord-9ac214ff101a4f35ac8c78b2744706c5
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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