Ethanol → tert-butyl N-[2-(4-hydroxypiperidin-4-yl)ethyl]carbamate

HRID 2155355Notes

Reaction equation

HRID 2155355 reaction equation
[CH3:25][CH2:26][OH:27].[OH-:28].[OH-:29].[OH:1][C:2]1([CH2:15][CH2:16][NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:3][CH2:4][N:5]([CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1.[Pd+2:30]>>[OH:1][C:2]1([CH2:15][CH2:16][NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 57599590tert-butyl N-[2-(1-benzyl-4-hydroxypiperidin-4-yl)ethyl]carbamate

Product 1

HCID 57599589tert-butyl N-[2-(4-hydroxypiperidin-4-yl)ethyl]carbamate

Sources & evidence

ORD record
ord-2232b0b2c3c04b719f50b0642b925376
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…