Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate → Tert-butyl 3-[4-bromo-3-(3-methoxypropoxy)benzyloxy]-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate
Reaction equation
[Br:35][c:36]1[c:37]([O:44][CH2:45][CH2:46][CH2:47][O:48][CH3:49])[cH:38][c:39]([CH2:42][Br:43])[cH:40][cH:41]1.[OH:1][CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1)[CH2:42][c:39]1[cH:38][c:37]([O:44][CH2:45][CH2:46][CH2:47][O:48][CH3:49])[c:36]([Br:35])[cH:41][cH:40]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-28ed66642f744ffbaefd62a928c5173a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…