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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2155435Generated: November 3, 2026

1,2-Dichloroethane → {2-[2-(2-Benzyloxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-piperidin-1-yl]-1-methyl-2-oxo-ethyl}-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/2155435

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-N-Boc-aminopropionic acidHCID 268471—
ReactantN-(N-tert-Butoxycarbonylpipecolyl)-4-amino-5-benzyloxy-2-oxo-tetrahydrofuranHCID 22977785—
Product{2-[2-(2-Benzyloxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-piperidin-1-yl]-1-methyl-2-oxo-ethyl}-carbamic acid tert-butyl esterHCID 22977789—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-607a31672a4040acbc79042083e3f897
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)