Acetonitrile → [4-(4-fluorobenzyl)piperidine-1-yl]-(6-hydroxy-1H-indole-2-yl)-methanone
Reaction equation
[CH3:28][C:29]#[N:30].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[cH:13][cH:14]1.[OH:15][c:16]1[cH:17][cH:18][c:19]2[cH:20][c:21]([C:25](=[O:26])[OH:27])[nH:22][c:23]2[cH:24]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:25]([c:21]3[cH:20][c:19]4[cH:18][cH:17][c:16]([OH:15])[cH:24][c:23]4[nH:22]3)=[O:26])[CH2:11][CH2:12]2)[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-e5af133e49ba49d2b472eac36fe696dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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