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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 215589Generated: November 1, 2026

Sodium ion → (2-{Difluoro-[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}-5-fluorophenyl)methanol

https://huagongshe.com/reaction/215589

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantTriphenylphosphineHCID 11776—
ReactantCarbonate IonHCID 19660—
ReactantPalladium ChlorideHCID 24290—
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant{2-[(4-Bromophenyl)(difluoro)methoxy]-5-fluorophenyl}methanolHCID 57864347—
Product(2-{Difluoro-[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}-5-fluorophenyl)methanolHCID 57864335—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-be165a9a6b7845b1abafba67bb43a1d9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)