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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2156036Generated: November 3, 2026

5-Fluoro-2-methylbenzenesulphonyl chloride → N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-5-fluoro-2-methylbenzenesulfonamide

https://huagongshe.com/reaction/2156036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methylbenzenesulphonyl chlorideHCID 136286—
Reactant4-[4-(3-Amino-2-fluorophenyl)-2-(1,1-dimethylethyl)-1,3-thiazol-5-yl]-2-pyrimidinamineHCID 57989709—
ReactantN-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1-methylethyl)-1,3-thiazol-4-yl]phenyl}-2,6-difluorobenzenesulfonamideHCID 57990030—
ProductN-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-5-fluoro-2-methylbenzenesulfonamideHCID 57989896—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-a1f3f28696ae4ba89d754735650d819c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)