Ethanol → [3'-(7-trifluoromethyl-3,4-dihydro-2H-quinolin-1-ylmethyl)-biphenyl-4-yl]-methanol

HRID 2156276Notes

Reaction equation

HRID 2156276 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][c:15]32)[cH:20][cH:21][cH:22]1.[C:34](=[O:35])([O-:36])[O-:37].[CH3:40][c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1.[CH3:47][CH2:48][OH:49].[Na+:38].[Na+:39].[OH:23][CH2:24][c:25]1[cH:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][cH:30]1>>[c:2]1(-[c:28]2[cH:27][cH:26][c:25]([CH2:24][OH:23])[cH:30][cH:29]2)[cH:3][c:4]([CH2:5][N:6]2[CH2:7][CH2:8][CH2:9][c:10]3[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][c:15]32)[cH:20][cH:21][cH:22]1

Participants

7

Reactant 6

HCID 702EthanolHCID 923Sodium ion2×HCID 1140TolueneHCID 19660Carbonate IonHCID 27347064-(Hydroxymethyl)benzeneboronic acidHCID 115958231-(3-Bromo-benzyl)-7-trifluoromethyl-1,2,3,4-tetrahydro-quinoline

Product 1

HCID 11603644[3'-(7-trifluoromethyl-3,4-dihydro-2H-quinolin-1-ylmethyl)-biphenyl-4-yl]-methanol

Sources & evidence

ORD record
ord-ce702399aefe49648e63e1b148530145
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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