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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2156411Generated: November 2, 2026

Tetrahydrofuran → 2-(3,4-Dichloro-phenyl)-3-[3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-propionic acid methyl ester

https://huagongshe.com/reaction/2156411

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 81646—
ReactantMethyl 2-(3,4-dichlorophenyl)acetateHCID 1268257—
ReactantDiisopropylamideHCID 5062348—
Reactant2-(3-Iodomethyl-cyclopentyloxy)-tetrahydropyranHCID 21959038—
Product2-(3,4-Dichloro-phenyl)-3-[3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-propionic acid methyl esterHCID 67482108—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-ccbbc86a96594f028ab08ea7e76bb60e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)