5-Bromothiophene-2-carbonitrile → 5-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile

HRID 2156462Notes

Reaction equation

HRID 2156462 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:7]#[N:8])[s:6]1.[CH3:9][C:10]1([CH3:24])[O:11][C:12](=[O:23])[NH:13][c:14]2[c:15]1[cH:16][c:17]([B:20]([OH:21])[OH:22])[cH:18][cH:19]2>>[c:2]1(-[c:17]2[cH:16][c:15]3[c:14]([cH:19][cH:18]2)[NH:13][C:12](=[O:23])[O:11][C:10]3([CH3:9])[CH3:24])[cH:3][cH:4][c:5]([C:7]#[N:8])[s:6]1

Participants

3

Reactant 2

HCID 35950595-Bromothiophene-2-carbonitrileHCID 10987806(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)boronic acid

Product 1

HCID 98789295-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-thiophene-2-carbonitrile

Sources & evidence

ORD record
ord-5ab7e4ed6b70480cacc20f7f52b9a66b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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