Potassium Cation → 5-{[tert-Butyl(dimethyl)silyl]ethynyl}-2-{[6-(morpholin-4-ylmethyl)pyridin-2-yl]amino}thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:7]1.[K+:33].[K+:34].[NH2:15][c:16]1[s:17][c:18]([C:24]#[C:25][Si:26]([CH3:27])([CH3:28])[C:29]([CH3:30])([CH3:31])[CH3:32])[cH:19][c:20]1[C:21](=[O:22])[NH2:23].[O-:35][C:36]([O-:37])=[O:38].[O:41]=[C:42]([CH:43]=[CH:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[CH:51]=[CH:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1.[O:59]=[C:60]([CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)[CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[Pd:39].[Pd:40]>>[c:2]1([NH:15][c:16]2[s:17][c:18]([C:24]#[C:25][Si:26]([CH3:27])([CH3:28])[C:29]([CH3:30])([CH3:31])[CH3:32])[cH:19][c:20]2[C:21](=[O:22])[NH2:23])[cH:3][cH:4][cH:5][c:6]([CH2:8][N:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5f68cd05975947e8a9e99e2fe50a9033
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…