Potassium Cation → (5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,6-difluoro-3-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl-methanol

HRID 2156700Notes

Reaction equation

HRID 2156700 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[n:9][cH:10]1.[CH3:34][OH:35].[F:11][c:12]1[c:13]([CH:14]=[O:15])[c:16]([F:30])[cH:17][cH:18][c:19]1[O:20][CH2:21][CH2:22][O:23][CH:24]1[O:25][CH2:26][CH2:27][CH2:28][CH2:29]1.[K+:32].[OH-:31].[OH2:33]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH:14]([c:13]3[c:12]([F:11])[c:19]([O:20][CH2:21][CH2:22][O:23][CH:24]4[O:25][CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:18][cH:17][c:16]3[F:30])[OH:15])[cH:6][nH:7][c:8]2[n:9][cH:10]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 962WaterHCID 103079325-bromo-1H-pyrrolo[2,3-b]pyridineHCID 58087257HCID 58087257, compound

Product 1

HCID 58087553(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,6-difluoro-3-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl-methanol

Sources & evidence

ORD record
ord-ef2b4f943939482c846ef11abf7d865d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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