5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 5-Amino-1-(cyclopropyl)-6,8-difluoro-1,4-dihydro-7-(3'-aminomethyl-4'-hydroxy-piperidin-1-yl)-4-oxo-quinoline-3-carboxylic acid
Reaction equation
[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([F:13])[c:11]1[F:12].[NH2:22][CH2:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28][CH:29]1[OH:30]>>[NH2:1][c:2]1[c:3]2[c:4](=[O:21])[c:5]([C:18](=[O:19])[OH:20])[cH:6][n:7]([CH:15]3[CH2:16][CH2:17]3)[c:8]2[c:9]([F:14])[c:10]([N:26]2[CH2:25][CH:24]([CH2:23][NH2:22])[CH:29]([OH:30])[CH2:28][CH2:27]2)[c:11]1[F:12]Participants
3
Sources & evidence
- ORD record
- ord-b5c7a06cf7cf4cc6954a3d229ee2151c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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