Bicarbonate Ion → methyl 3-cyclohexyl-2-{2-[2-(tetrahydropyran-2-yloxy)ethylsulfanyl]phenyl}-1H-indole-6-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([S:8][CH2:9][CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1.[C:18](=[O:19])([O-:20])[OH:21].[CH3:51][O:52][CH2:53][CH2:54][O:55][CH3:56].[CH:23]1([c:29]2[c:30]([B:42]3[O:43][C:44]([CH3:45])([CH3:46])[C:47]([CH3:48])([CH3:49])[O:50]3)[nH:31][c:32]3[cH:33][c:34]([C:38](=[O:39])[O:40][CH3:41])[cH:35][cH:36][c:37]23)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[Na+:22].[OH2:57].[cH:58]1[cH:59][cH:60][c:61]([P:62]([Pd:63]([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[P:102]([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)([c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[c:127]2[cH:128][cH:129][cH:130][cH:131][cH:132]2)[cH:133][cH:134]1>>[c:2]1(-[c:30]2[c:29]([CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]3)[c:37]3[c:32]([nH:31]2)[cH:33][c:34]([C:38](=[O:39])[O:40][CH3:41])[cH:35][cH:36]3)[c:3]([S:8][CH2:9][CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:4][cH:5][cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8ca998842fa449bfa885a23a07913a54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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