Pyridine → N-[3-fluoro-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen-7-yl]methanesulfonamide

HRID 2157042Notes

Reaction equation

HRID 2157042 reaction equation
[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[F:6][C:7]1=[C:16]([c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)[c:15]2[c:10]([cH:11][c:12]([NH2:24])[cH:13][cH:14]2)[O:9][C:8]1([CH3:25])[CH3:26].[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[CH3:1][S:2](=[O:4])(=[O:5])[NH:24][c:12]1[cH:11][c:10]2[c:15]([cH:14][cH:13]1)[C:16]([c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)=[C:7]([F:6])[C:8]([CH3:25])([CH3:26])[O:9]2

Participants

4

Reactant 3

HCID 1049PyridineHCID 31297Methanesulfonyl chlorideHCID 59442934HCID 59442934, compound

Product 1

HCID 25183423N-[3-fluoro-4-(4-fluorophenyl)-2,2-dimethyl-2H-chromen-7-yl]methanesulfonamide

Sources & evidence

ORD record
ord-9be29dfe275f45669322825c6b4a6058
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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